Three chimps are sent into space to explore the possibility of alien life when an unmanned space shuttle crash lands on an uncharted planet.
Andy Samberg
as Ham III (voice)
Cheryl Hines
as Luna (voice)
Jeff Daniels
as Zartog (voice)
Patrick Warburton
as Titan (voice)
Kristin Chenoweth
as Kilowatt (voice)
Kenan Thompson
as Ringmaster (voice)
Zack Shada
as Comet / Nava Boy (voice)
Carlos Alazraqui
as Houston (voice)
Omid Abtahi
as Dr. Jagu (voice)
Patrick Breen
as Dr. Bob (voice)
Jane Lynch
as Dr. Poole (voice)
Kath Soucie
as Dr. Smothers (voice)
