Following a bomb scare in the 1960s that locked the Webers into their bomb shelter for 35 years, Adam now ventures forth into Los Angeles to obtain food and supplies for his family, and a non-mutant wife for himself.
Brendan Fraser
as Adam
Alicia Silverstone
as Eve
Christopher Walken
as Calvin
Sissy Spacek
as Helen
Dave Foley
as Troy
Joey Slotnick
as Soda Jerk
Rex Linn
as Dave
Deborah Kellner
as Miss Sweet
Nathan Fillion
as Cliff
Jenifer Lewis
as Dr. Aron
Cynthia Mace
as Betty
Don Yesso
as Jerry