Though a childhood bout with polio left him dependent on an iron lung, Mark O'Brien maintains a career as a journalist and poet. A writing assignment dealing with sex and the disabled piques Mark's curiosity, and he decides to investigate the possibility of experiencing sex himself. When his overtures toward a caregiver scare her away, he books an appointment with sex surrogate Cheryl Cohen-Greene to lose his virginity.
John Hawkes
as Mark
Helen Hunt
as Cheryl
William H. Macy
as Father Brendan
Moon Bloodgood
as Vera
Annika Marks
as Amanda
Adam Arkin
as Josh
Rhea Perlman
as Mikvah Lady
W. Earl Brown
as Rod
Robin Weigert
as Susan
Blake Lindsley
as Dr. Laura White
Ming Lo
as Clerk
Rusty Schwimmer
as Joan
