In the 1840s, Ramsey MacKay, the driver for the struggling Wells Fargo mail and freight company, will secure an important contract if he delivers fresh oysters to Buffalo from New York City. When he rescues Justine Pryor and her mother, who are stranded in a broken wagon on his route, he doesn't let them slow him down and gives the ladies an exhilirating ride into Buffalo. He arrives in time to obtain the contract and is then sent by company president Henry Wells to St. Louis to establish a branch office.
Joel McCrea
as Ramsay MacKay
Bob Burns
as Hank York, a wanderer
Frances Dee
as Justine Pryor
Lloyd Nolan
as Dal Slade
Henry O'Neill
as Henry Wells
Mary Nash
as Mrs. Pryor
Ralph Morgan
as Nicholas Pryor
Johnny Mack Brown
as Talbot Carter
Porter Hall
as James Oliver
Jack Clark
as William Fargo
Clarence Kolb
as John Butterfield
Robert Cummings
as Dan Trimball, prospector