When video creator Angie knocks on the door of the City Hunter detective agency looking for a missing cat, Ryo Saeba and Kaori Makimura think they have a simple case on their hands. But an attempt on Angie's life changes the game, leaving Ryo in the crosshairs of mysterious assassins on the trail of Angel Dust, a military technology capable of creating super soldiers. Under the watchful eye of his adoptive father Kaibara, Ryo will have to deal with a past he has tried to escape for too long.
神谷明
as Ryo Saeba (voice)
伊倉一恵
as Kaori Makimura (voice)
麻上洋子
as Saeko Nogami (voice)
小山茉美
as Miki (voice)
玄田哲章
as Umibozu (voice)
深見梨加
as Rui Kisugi (voice)
堀内賢雄
as Shin Kaibara (voice)
Ryo Ito
as Boat Landing Man (voice)
木村昴
as Espada (voice)
桐本拓哉
as Makoto Shimoyamada (voice)
北川里奈
as Umikobozu (voice)
栗田貫一
as Lupin III (voice)
