When he was 12 years old, Bill Cody, later knew as Buffalo Bill, is rider for "pony express" carrying the mail through the wilds of America. It becomes later caravans guide. When driving one of them meets Luisa, the niece of a priest who tried to evangelize the savage tribes accompanied by a converted Indian. It is a dangerous time because, before the advancing white man, the Sioux tribes are buying weapons from unscrupulous dealers...
Rik Van Nutter
as Buffalo Bill Cody
Adrian Hoven
as Wild Bill Hickok
Gloria Milland
as Calamity Jane
Francisco Sanz
as Pastor Norman Lieberman
Helga Sommerfeld
as Ethel Lieberman
Carlos Romero Marchent
as Ted
Alejandra Nilo
as Luisa
Raf Baldassarre
as Guillermo
Alfonso Rojas
as Colonel Carr
Antonio Molino Rojo
as Dittle
Kurt Großkurth
as St. James
Mery Leyva
as Agnes St. James