Three lifelong best friends known as “The Supremes” share the unbreakable bonds of sisterhood from decades of weathering life’s storms. Through the joys and sorrows of life, marriage and children, happiness and blues, love and loss, new shades of heartbreak and illness threaten to stir up the past when the trio sees their bond put to the test as they face their most challenging times yet.
Aunjanue Ellis-Taylor
as Odette Henry
Sanaa Lathan
as Barbara Jean Maxberry
Uzo Aduba
as Clarice Baker
Mekhi Phifer
as James Henry
Julian McMahon
as Chick Carlson
Vondie Curtis-Hall
as Lester Maxberry
Russell Hornsby
as Richmond Baker
Kyanna Simone Simpson
as Odette (Young)
Tati Gabrielle
as Barbara Jean (Young)
Abigail Achiri
as Clarice (Young)
Dijon
as James (Young)
Cleveland Berto
as Lester (Young)
